Researchers found that targeting cFLIP re-sensitized lymphoma cells to death signals in preclinical mouse models of DLBCL.

Capsaicin, the bioactive compound responsible for the characteristic spiciness of chilli peppers, has attracted considerable attention for its anticancer properties. In various cancer cell types, ...

Our cells are constantly making life-or-death choices, guided by intricate molecular pathways like apoptosis. This highly ...

A research team at the University of Cologne's Center for Molecular Medicine Cologne (CMMC) has discovered that the protein ...

Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...

Necrotic cell death is a fundamental biological process, yet the terminal execution mechanisms of necrosis are still not fully understood. The team dissected different types of cell death at ...

After cells die, they leave a residue that sends messages to other cells in ways that are valuable to the immune system. But this process can also be hijacked by viruses such as influenza, according ...

A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival, revealing a potential strategy for selectively targeting tumours associated with ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in ACS Nano, how proteins in cells can be controllably activated through heating, an effect that can be used ...

A precision cancer strategy that selectively kills tumour cells while leaving healthy tissue intact may be within reach for the majority of colorectal cancer patients, according to new research ...