Tuberous sclerosis complex was once thought to be a rare disease but is now known to occur in about 1 in 6000 live births, [18] making it not quite as common as neurofibromatosis type 1 (1 in 4,000 ...
We provide a comprehensive panel that includes sequencing and deletion/duplication analysis for the TSC1 and TSC2 gene. Single gene sequencing and deletion/duplication analysis is also available for ...
Lisa Ratledge can still remember the sleepless nights fueled by the fear that her young son might have a seizure while she was asleep and die in his bed. She became tearful at the memory of her son, ...
Tuberous sclerosis complex (TSC) is a rare genetic disease (approximate 1:6,000 birth incidence) with a wide variability of physical and neuropsychiatric symptoms. Patients require lifelong care from ...
Cassava Sciences Inc. a has reported positive preclinical results of a study evaluating simufilam in a mouse model of tuberous sclerosis complex (TSC)-related epilepsy. TSC is a rare genetic disorder ...
RADNOR, Pa.--(BUSINESS WIRE)--Marinus Pharmaceuticals, Inc. (Nasdaq: MRNS), a pharmaceutical company dedicated to the development of innovative therapeutics to treat seizure disorders, today announced ...
A common misconception about rare disorders is that they only effect a small number of people. However, according to the National Organization for Rare Disorders, around 25-30 million Americans are ...
The Company plans to discontinue further clinical development of ganaxolone in TSC. Marinus Pharmaceuticals announced that its phase 3 trial of ganaxolone did not meet the primary end point for the ...
In early childhood, a woman developed multiple red papules on the nose and cheeks with the appearance of angiofibromas (see Figure 1). As an adult, papules formed around her toes which were consistent ...