The Rho-family GTPase Rac1 activates the WAVE regulatory complex (WRC) to drive Arp2/3 complex-mediated actin polymerization in many essential processes. Rac1 binds to WRC at two distinct sites—the A ...
Cell migration is a critical process for animal cells, especially in the embryo, but also in the adult. For example, immune cells constantly patrol the organism to fight infections. Nucleation of ...
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